Institute Research Publications
    (1989 - 2002)

 

A.S. Cohen, D.R. Najarian, A. Paulus, A. Guttman, J.A. Smith, B.L. Karger: "Rapid Separation and Purification of Oligonucleotides by High Performance Capillary Gel Electrophoresis," Proc. Nat. Acad. Sci., 85, 9660 (1989). 
B.L. Karger, A. Cohen, A. Guttman: "Capillary Electrophoresis in the Biological Sciences," Biomed. Appl., 492, 585 (1989). 
A. Guttman, A.S. Cohen, D.N. Heiger, B.L. Karger: "Analytical and Micropreparative Ultra-High Resolution of Oligonucleotides by Polyacrylamide Gel High Performance Capillary Electrophoresis," Anal. Chem., 62, 137 (1990). 
D.N. Heiger, A.S. Cohen, B.L. Karger: "The Separation of DNA Fragments by High Performance Capillary Electrophoresis with Low and Zero Crosslinked Polyacrylamide Using Continuous and Pulsed Electric Fields," HPLC'90 Symposium Volume, J. Chromatogr., 516, 33 (1990). 
B.L. Karger, F. Foret: "Capillary Electrophoresis: Introduction and Assessment," Capillary Electrophoresis: Therory, Methodology and Applications, Chapter 1, ed., N. Guzman, Marcel Dekker, New York, NY, pp. 3-63 (1993). 
M.C. Ruiz-Martinez, J. Berka, A. Belenkii, F. Foret, A.W. Miller, B.L. Karger: "DNA Sequencing Using Capillary Electrophoresis with Replaceable Linear Polyacrylamide and Laser Induced Fluorescence Detection," Anal. Chem., 65, 2851 (1993). 
K. Shimura, B.L. Karger: "Affinity Probe Capillary Electrophoresis: Analysis of Recombinant Human Growth Hormone with a Fluorescent Labelled Antibody Fragment," Anal. Chem., 66, 9 (1994). 
K. Khrapko, J.S. Hanekamp, W.G. Thilly, A. Belenkii, F. Foret, B.L. Karger: "Constant Denaturant Capillary Electrophoresis (CDCE): A High Resolution Approach to Mutational Analysis," Nucl. Acids Res., 22, 364 (1994). 
R.S. Markiewicz: "Van Hove Exciton Kageons and High-Tc Superconductivity: XA. The Role of Spin-Orbit Coupling in Generating a Diabolical Point," Physica C, 228, 227 (1994). 
K.Z. Ismail, M.A. El-Sayed, A.-M. Al-Kouraty, G. Davies: "Transmetalation of Targets (m-Y)N4Cu2ICu2IIC14 and (m-Y,m-O)N4Cu4Cl4 (Y = 3,4,5,6-Tetrachlorocatecholate) with M(NS)2 Reagents," Inorg. Chim. Acta, 217, 85 (1994). 
M.A. El-SayedT.A. El-Zaiate, G. Davies: "Unusually Stable Peroxocopper Complexes. Stoichiometry. Products and Kinetics of Oxidation of the Dimeric Copper (I) Complex [LCuBr]2 (L=N, N1-Diethylethylenediamine) by Dioxygen in Methylene Chloride from -51 - 30°C" Inorg. Chim. Acta, 217, 109 (1994).
R.W. Giese, M. Saha, S. Abdel-Baky, K. Allam: "Measuring DNA Adducts by GC-EC-MS: An Example of Trace Organic Analysis," Meth. in Enzymol., in press (1996). 
B.C. Giessen: "Alloys," Encyclopedia of Inorganic Chemistry, R.B. King, Editor-in-Chief, Wiley-Interscience, New York, NY (1995).
S.L. Wu and B.L. Karger: "Hydrophobic Interaction Chromatography", Chapter 2, Methods in Enzymology Vol. 270: High Resolution Separaton and Analysis of Biological Macromolecules (1996).
S.M. Wolf, P. Vouros: "Application of Capillary Liquid Chromatography-Mass Spectrometry Coupled with Tandem Mass Spectrometric Methods to the Rapid Screening of Adducts Formed in the Reaction of N-Acetoxy-2-acetylaminofluorene with Calf Thymus DNA," Chemical Research in Toxicology, 7, 82 (1994). 
M. Itani, R.W. Giese: "Extractive Hydrogenation: A New and Versatile Technique Broadening Gas Chromatography Applications," Anal. Chem., 66, 1189 (1994). 
M. Annan, P. Vouros: "A Comparison of the Reactions of the Oxide Radical Anion (O-.) with Simple Aromatic Compounds at Atmospheric and at Reduced Pressure Conditions," J. Amer. Soc. for Mass Spec., 5, 367 (1994). 
W. Nashabeh, K.F. Greve, D. Kirby, F. Foret, B.L. Karger, D.H. Reifsnyder, S.H. Builder: "Incorporation of Hydrophobic Selectivity in Capillary Electrophoresis: Analysis of Recombinant Insulin-like Growth Factor I Variants," Anal. Chem., 66, 2148 (1994). 
J. Barry, P. Vouros, A. Van Schepdael, S.-J. Law: "Mass and Sequence Verification of Modified Oligonucleotides Using Electrospray Tandem Mass Spectrometry," J. Mass Spectrom., 30, 993 (1995). 
R.S. Markiewicz: "Van Hove Jahn-Teller Effect and High-Tc Superconductivity," Physica B, 194-6, 1461 (1994). 
J.Z. Zhang, S.Q. Wang, B. Maheswaran, C. Testelin, C. Bonetto, R. Hidalgo, X.-Y. Zhang, B.C. Giessen, R.S. Markiewicz: "Effect of Excess BaCuBCO2 on Grain Boundaries of Melt-Regrown EuBa2Cu3O7-d," Physica B, 194-6, 1934 (1994). 
E.A. Ghabbour, A.H. Khairy, D.P. Cheney, V. Gross, G. Davies, T.R. Gilbert, X.-Y. Zhang: "Isolation of Humic Acid from the Brown Alga Pilayella Littoralis," J. Applied Phycology, 6, 459 (1994). 
K.F. Greve, W. Nashabeh, B.L. Karger: "Use of Zwitterionic Detergents for the Separation of Closely Related Peptides by Capillary Electrophoresis," J. Chromatogr., 680, 15 (1994). 
F. Foret, T. Thompson, P. Vouros, B.L. Karger, P. Gebauer, P. Bocek: "Liquid Sheath Effect in the Capillary Electrophoresis/Electrospray-Mass Spectrometric Analysis of Proteins," Anal. Chem., 66, 4450 (1994). 
R.S. Markiewicz: "Topicological Significance of Saddle Point Van Hove Singularity: Comparison of Orbital Switching and Magnetic Breakdown," J. Superconductivity, 7, 803 (1994). 
Y. Bi, J.M. Cook, P.W. Le Quesne: "A Partial Synthesis of the Alstonia Bisindole Alkaloid Villalstomine," Tetrahedron Letters, 35, 3877 (1994). 
A.N. MacInnes, A.R. Barron, J.J. Li, T.R. Gilbert: "Reaction Bonded Refractory Metal Carbide/Carbon Composites," Polyhedron, 13, 1315 (1994). 
X.W. Crowley, V. Murugaiah, A. Naim, R.W. Giese: "Masking as a Mechanism for Evaporative Loss of Trace Analyte, Especialy After Solid-Phase Extraction," J. Chromatogr., 699, 395 (1995).
B.L. Karger, D. Schmalzing, F. Foret: "Siloxandediol Coating for Capillary Electrophoresis and for General Surface Modification," U.S. Patent No. 5,322,608 (1994). 
B.L. Karger: "Capillary Electrophoresis: Current and Future Directions," Amer. Lab 25, 16, 23 (1994). 
J.B. Carlson, G. Davies, P. Vouros: "A Study of Heterotetranuclear Transmetalation Products by Fast Atom Bombardment Mass Spectrometry," Inorg. Chem., 33, 2334 (1994). 
J. Berka, Y.F. Pariat, O. Muller, K. Hebenbrock, D.N. Heiger, F. Foret, B.L. Karger: "Sequence Dependent Migration Behavior of dsDNA in Capillary Electrophoresis," Electrophoresis, 16, 377 (1995).
B.L. Karger, Y.-H. Chu, F. Foret: "Capillary Electrophoresis of Proteins and Nucleic Acids," Ann. Rev. of Bioph. and Biomol. Struc., 24, 579 (1995).
X.-Y. Zhang, R.Q. Hidalgo, R.J. Murphy, R.S. Markiewicz, B.C. Giessen: "Grain Refinement, Texture Formation and Amorphization of Fullerene in Mechanically Alloyed Metal-Fullerene Combinations," in Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials, K.M. Kadish, R.S. Ruoff, eds., El. Chem. Soc. Fullerene Symp. Proc., 94-24, The Electrochemical Society, Inc., Pennington, NJ, 623 (1994). 
S.Q. Wang, J.Z. Zhang, C. Bonetto, B. Maheswaran, M.G. Williams, I. Weber, R.S. Markiewicz, B.C. Giessen: "Biaxial Alignment of High-Tc Superconductor Polycrystals VII: Demonstration of Biaxial Alignment of EuBa2Cu3Ox (Eu-123) by Pole Figure Measurement, Appl. Supercond., 3, 27 (1995). 
B. Maheswaran, M.G. Williams, J.Z. Zhang, S.Q. Wang, C.A. Bonetto, I. Heyvaert, C. Testelin, R.S. Markiewicz, B.C. Giessen: "Terrace Growth in Partially Melt-Regrown EuBa2Cu3O7-dHigh-Tc Superconductors," J. of Superconductivity, 9, 135 (1995). 
B. Yeung, P. Vouros, M.-L. Siu-Caldera, G. Reddy: "Characterization of the Metabolism of 1,25-Dihydroxy-16-Ene Vitamin D3 in Rat Kidney by Capillary HPLC-Electrospray/Tandem Mass Spectrometry," Biochem. Pharmacol., 49, 1099 (1995). 
A. Gutman, C.-H. Shieh, B.L. Karger, S.J. Pentoney, Jr., K.D. Konrad, S. Rampal, K. Ganzler: "Capillary Column Containing Removable Separation Gel Composition and Method of Use," U.S. Patent No. 5,370,777 (1994). 
B.L. Karger: "Capillary Electrophoresis: The Launching of a New Journal," J. Cap. Electro., 1, 124 (1994). 
B.L. Karger, K. Shimura: "Method for Quantitating Trace Amounts of an Analyte in a Sample by Affinity Capillary Electrophoresis," U.S. Patent No. 5,348,633 (1994). 
S.M. Wolf, P. Vouros: "Incorporation of Sample Stacking Techniques into the Capillary Electrophoresis CF-FAB Mass Spectrometric Analysis of DNA Adducts," Anal. Chem., 67, 891 (1995). 
D. Rindgen, R.J. Turesky, P. Vouros: "Analysis of In Vitro Formed DNA Adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Using Capillary Liquid Chromatography - Electrospray Ionization/Tandem Mass Spectrometry," Chem. Res. Toxicol., 8, 1005 (1995). 
  P.W. Le Quesne, M. Moussa, D.A. Forsyth: "Structural and Synthetic Studies of Pithomycolide," Pure & Appl. Chem., 66 (10/11), 2249 (1994). 
P.A. Mabrouk: "The Effect of Pegylation on the Structure and Function of Horse Cytochrome c," Bioconjugate Chem., 5, 236 (1994). 
Y.-H. Ho, D. Kirby, B.L. Karger: "Free Solution Identification of Candidate Peptides from Combinatorial Libraries by Affinity Capillary Electrophoresis/Mass Spectrometry," J. Amer. Chem. Soc., 117, 5419 (1995).
X.Y. Zhang, R.Q. Hidalgo, R.J. Murphy, R.S. Markiewicz, B.C. Giessen: "The Effects of Mechanical Alloying of C60 with Metals (II): Al and Mg," Science and Technology of Fullerenes Materials, P. Bernier, D.S. Bethune, L.W. Chiang, T.W. Ebbesen, R.W. Metzger, J.W. Mintmire, eds., MRS Symp. Proc. Vol. 359, MRS, Pittsburgh, PA, (1995) 437. 
R. Hidalgo, X.Y. Zhang, B.C. Giessen: "The Binary Phase Diagram Naphthalene- C60," Science and Technology of Fullerenes Materials, P. Bernier, D.S. Bethune, L.W. Chiang, T.W. Ebbesen, R.W. Metzger, J.W. Mintmire, eds., MRS Symp. Proc. Vol. 359, MRS, Pittsburgh, PA, (1995) 561. 
S. Williams, C. Schwer, A.S.M. Krishnarao, C. Heid, B.L. Karger, P.M. Williams: "Quantitative Competetive PCR: Analysis of Amplified Products of the HIV-1 gag Gene by Capillary Electrophoresis with Laser-Induced Fluorescence Dectection," Anal. Chem., 236, 146 (1996). 
K. Hebenbrock, P.M. Williams, B.L. Karger: "SSCP Using Capillary Electrophoresis with Two-Dye Laser-Induced Fluorescence Detection," Electrophoresis, 16, 1429 (1995). 
O. Muller, F. Foret, B.L. Karger: "Design of a High Precision Fraction Collector for Capillary Electrophoresis," Anal. Chem., 67, 2974 (1995). 
R.W. Giese: "Molecular Analytical Release Tags and Their Use in Chemical Analysis," U.S. Patent No. 5,360,819 (1994). 
S. Nubberger, F. Foret, S.C. Herbert, B.L. Karger, M.A. Hediger: "Non- radioactive Monitoring of Organic and Inorganic Solute Transport into Single Xenopus oocyts by Capillary Zone Electrophoresis," Biophysical J., 70, 998 (1996). 
S.-Q. Wang, R.A. Bigelow, J.-Z. Zhang, C. Bonetto, B. Maheswaran, M.G. Williams, R.S. Markiewicz, B.C. Giessen: "Biaxial Alignment of High-Tc Superconductors Polycrystals VIII: Phi-Circle Scan of EuBa2Cu3O7-d (Eu-123),"J. Mater. Res., 11, 1108 (1996). 
O. Muller, F. Foret, J. Thorne, W. Goetzinger, B.L. Karger: "Analysis of Protein Fractions by Micropreparative Capillary IEF and MALDI/TOF," J. Chromatogr. HPCEí95 Volume, 716, 157 (1995). 
R.S. Markiewicz: "Van Hove Exciton-Cageons and High-Tc Superconductivity: XB: Polaronic Coupling in the Doped Material," Physica C, 255, 211 (1995). 
S.P. Kounaves, A. Robbat, Jr., G. Davies: "Metal, Metal Alloy, and Metal Oxide Formation by Electrodeposition of Polymetallic Complexes," U.S. Patent No. 5,277,789 (1994). 
D.P. Cheney, L.Z. Wang: "Method of Causing Somatic Hybridization Between Two Species of Algae," U.S. Patent No. 5,365,018 (1994). 
J. Cunniff, D. Kaplan, S. Fossi, P. Vouros: "Evidence for Direct Desorption of Crown Ether Complexes via Liquid Secondary Ion Mass Spectrometry," J. Am. Soc. Mass Spectrom., 5, 638 (1994). 
J.B. Cunniff, P. Vouros, D.L. Kaplan, S.A. Fossey: "The Origin and Ion Spectra of Noncovalent Peptide Dimers Observed in Liquid Secondary Ion Mass Spectrometry Explained via First-order Gas-phase Kinetics," Biol. Mass Spectrom., 23, 741 (1994). 
J.B. Cunniff, P. Vouros: "Mass and Charge Assignment for Electrospray Ions by Crown Ether Adduction," Rapid Commun. Mass Spectrom., 8, 715 (1994). 
S.L. Ablaza, N.N. Pai, P.W. Le Quesne: " Quararibea Metabolites. 2. Efficient Synthetic Approaches to (+) - (2S, 3S, 4R)-g-Hydroxyisoleucine, the Characteristic Quararibea Amino Acid," Nat. Products Letters, 6, 77 (1995). 
J.B. Cunniff, P. Vouros: "False Positives and the Detection of Cyclodextrin Inclusion Complexes by Electrospray Mass Spectrometry," J. Am. Soc. Mass Spectrom., 6, 437 (1995). 
K. Greve, D. Hughes, P. Richberg, M. Kats, B.L. Karger: "Liquid Chromatography and Capillary Electrophoretic Examination of Intact and Degraded Fusion Protein CTLA4Ig and Kinetics of Inter-Conformational Transition," J. Chromatography, 723, 273 (1996). 
B. Yeung, P. Vouros, "The Role of Mass Spectrometry in Vitamin D Research," Mass Spectrometry Reviews, 8, 179 (1995)
J. Barry, J. Muth, S.-J. Law, B.L. Karger and P. Vouros: "Analysis of Modified Oligonucleotides by Capillary Electrophoresis in a Polyvinylpyrrolidone Matrix Coupled with Electrospray Mass Spectrometry," J. Chromatogr. A., 732, 159 (1996).
P. Vouros, Y. Dunayevskiy, T. Carell, E.A. Winter, J. Rebek, Jr.: "Characterization of the Complexity of Small Molecule Libraries by Electrospray Ionization Mass Spectrometry," Anal. Chem., 67, 2906 (1995). 
M. Saha, A. Abushamaa, R.W. Giese: "General Method for Determining Ethylene Oxide and Related N7 - Guanine DNA Adducts by Gas Chromatography-Electron Capture Mass Spectrometry," J. Chromatogr., 712A, 345 (1995).
A.H. Khairy, G. Davies, H.Z. Ibrahim, E.A. Ghabbour: "Adsorption of Aqueous Nucleobases, Nucleosides and Nucleotides on Compost-Derived Humic Acid. 1. Naturally Occuring Pyrimidines," J. Phys. Chem., 100, 2410 (1996). 
A.H. Khairy, G. Davies, H.Z. Ibrahim, E.A. Ghabbour: "Adsorption of Aqueous Nucleobases, Nucleosides and Nucleotides on Compost-Derived Humic Acid. 2. Naturally Occuring Purines1," J. Phys. Chem., 100, 2417 (1996). 
  M.C. Ruiz-Martinez, E. Carrilho, J. Berka, J. Kieleczawa, A.W. Miller, F. Foret, S. Carson, B.L. Karger: "Fluorescence DNA Sequencing by Capillary Electrophoresis Using Short Oligonucleotide Primer Libraries," Biotechniques, 20, 1058 (1996). 
P. Wang, R.W. Giese: "Phosphate-Specific Fluorescence Labeling of Pepsin by BO-IMI," Anal. Biochem., 230, 329 (1995).
J. Muth, O. Muller, J. Berka, J.T. Leonard, and B.L. Karger, "DNA Sequence Analysis of Prinker-Modified Restriction Fragments after Collection from Capillary Electrophoresis with Replaceable Matrices", J. Chromatogr. A., 744, 303 (1996).
P. Wang, V. Murugaiah, B. Yeung, P. Vouros, R.W. Giese, "2-Phosphoglycolate and glycolate-electrophore detection, including detection of 87 zeptomoles of the latter by gas chromatography-electron-capture mass spectrometry," J. of Chroma. A, 721, 289 (1996
K. Greve, D.E.Hughes, B.L. Karger, "Capillary Electrophoretic Examination of Underivatized Oligosaccharide Mixtures Released from Immunoglobulin G Antibodies and CTLA4Ig Fusion Protein," J. Chromatogr. A, 749, 237 (1996).
B.L. Karger, "HPLC: Early and Recent Perspectives," J. Chem. Ed., 74, 45 (1997)
Y.-H. Chu, Y.M. Dunayevskiy, D.P. Kirby, P. Vouros, B.L. Karger, "ACE/MS for Screening Combinatorial Libraries,"J. Amer. Chem. Soc., 118, 7827 (1996).
B. L. Karger, F. Foret, J. Berka, "Capillary Electrophoresis with Polymer Matrices: DNA and Protein Separation and Analysis," Chapter 13, Methods in Enzymology Vol. 271: High Resolution Separaton and Analysis of Biological Macromolecules (1996).
J. A. Thorne, W. Goetzinger, A. Chen, K. Moorehouse, B.L. Karger, "Examination of Capillary Zone Electrophoresis, Capillary Isoelectric Focusing and Sodium Dodecyl Sulfate Capillary Electrophoresis for the Analysis of Recombinant Tissue Plasminogen Activator," J. Chromatogr.A, 744, 155 (1996).
E. Carrilho, M. C. Ruiz-Martinez, J. Berka, I. Smirnov, W. Goetzinger, A.W. Miller, D. Brady, B.L. Karger, "Rapid DNA Sequencing of More Than 1,000 Bases Per Run by Capillary Electrophoresis Using Replaceable Linear Polyacrlamide Solutions," Anal. Chem., 68, 3305 (1996).
D. Kirby, J.M. Thorne, W.K. Goetzinger and B.L. Karger: "A CE-ESI-MS Interface for Stable, Low-Flow Operation," Anal. Chem., 68, 4451 (1996).
R. Giese, A. Abushamaa, A. Naim: "Satellite High-Performance Liquid Chromatography for Trace Sample Cleanup," J. of Chroma. A., 742, 295 (1996)
M.M. Moussa, P.W. Le Quesne: "Total Synthesis of the Cyclodepsipeptide Ionophore Pithomycolide," Tetrahedron Letters, 37, 6479 (1996).
S.-X. Yu, P.W. Le Quesne: "Quararibea Metabolites. 3.1 Total Synthesis Of (±) - Funebral, A Rotationally Restricted Pyrrole Alkaloid, Using A Novel Paal-Knorr Reaction," Tetrahedron Letters, 36, 35, 6205 (1995).


Rashkovetsky, L.G., Lyubarskaya, Y.V., Foret, F., Hughes, D.E., and Karger, B.L., “Automated Microanalysis Using Magnetic Beads with Commercial Capillary Electrophoretic Instrumentation”, J. Chromatogr. A., 781, 197-204 (1997).

Suzuki, H., Müller, O., Guttman, A. and Karger, B.L., “Analysis of 1-Aminopyrene-3,6,8-Trisulfonate (APTS) Derivatized Oligosaccharides by Capillary Electrophoresis with Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry”, Anal. Chem., 69, 4554-4559 (1997).

Xue, Q., Dunayevskiy, Y.M., Foret, F. and Karger, B.L., "Integrated Multichannel Microchip
Electrospray Ionization Mass Spectrometry: Analysis of Peptides from On-chip Tryptic Digestion of Melittin", Rapid Communications in Mass Spec., 11, 1253-1256 (1997).

Piggee, C.A., Muth, J., Kotler, L., Carrilho, E., Ruiz-Martinez, M.C. and Karger, B.L., "Capillary Electrophoresis for the Detection of Known Point Mutations by Single Nucleotide Primer Extension and Laser-Induced Fluorescence Detection", J. Chromatogram. A, 781, 367-375 (1997).

Lyubarskaya, Y., Dunayevskiy, Y., Vouros, P. and Karger, B.L., “Microscale Epitope Mapping By Affinity Capillary Electrophoresis - Mass Spectrometry”, Anal. Chem., 69, 3008-3014 (1997).

Xu, L., Bian, N., Wang, Z., Abdel-Baky, S., Pillai, S., Magiera, D., Murugaiah, V., Giese, R.W., Wang, P., O’Kecffe, T., Abushamaa, H., Kutney, L., Church, G., Carson, S., Smith, D., Park, M., Wronka, J. and Laukien, F., Electrophore Mass Tag Dideoxy DNA Sequencing, Anal. Chem., 69, 3595-3602 (1997).

Shen, X. and Giese, R.W., Hydrazide as a Ligand Moiety in Immobilized Metal Ion Affinity Chromatography: Separation of BO-IMI and BODIPY-Hydrazide, J. Chromatogr. A, 777, 261-265 (1997).

Bian, N., Wang, P., Wang, Z., Xu, L., Church, G. and Giese, R.W., Detection Via Laser Desorption and Mass Spectrometry of Multiplex Electrophore-Labeled Albumin, Rapid Commun. in Mass Spectrom. 11, 1781-1784 (1997).

N-Hydroxysuccinimide ester labeling 5’-aminoalkyl DNA oligomers: reaction conditions and purification, Wang, Z., Bian, N., Qian, X. and Giese, R.W., Journal of Chromatogr. A, 806 (1998) 93-95.

El Rassi, Z. and Giese, R.W., eds, Selectivity and Optimization in Capillary Electrophoresis, 1997, Elsevier, Amsterdam.


Karger, B.L., “Capillary Electrophoresis: Overview and Perspective”, High Performance Capillary Electrophoresis: Theory, Techniques, and Applications, M.G. Khaledi, ed., John Wiley & Sons, N.Y., N.Y. (1998) 3-24.

Goetzinger, W., Kotler, L., Mitnik, L., Carrilho, E., Ruiz-Martinez, M., Salas-Solano, O. and Karger, B.L., “Characterization of High Molecular Weight Linear Polyacrylamide Powder Prepared by Emulsion Polymerization as a Replaceable Polymer Matrix for DNA-Sequencing by Capillary Electrophoresis”, Electrophoresis, 19, 242-248 (1998).

Ruiz-Martinez, M.C., Salas-Solano, O., Carrilho, E. and Karger, B.L., "DNA Sequencing Analysis for CE Using Replaceable Polymer Solutions. Part A: Sample Purification Method for Rugged and High Performance Sequence Analysis", Anal. Chem., 70, 1516-1527 (1998).

Salas-Solano, O., Ruiz-Martinez, M.C., Carrilho, E., Kotler, L. and Karger, B.L. "DNA Sequencing Analysis for CE Using Replaceable Polymer Solutions. Part B: Quantitative Determination of the Role of Sample Matrix Components on Sequencing Analysis", Anal. Chem., 70, 1528-1535 (1998).

Guttman, A., Shieh, P. and Karger, B.L., "Capillary SDS Gel Electrophoresis of Proteins" in Practical Approach Series: Capillary Gel Electrophoresis of Proteins, in press (1998).

Dunayevskiy, Y.M., Lyubarskaya, Y.V., Chu, Y.-H., Vouros, P. and Karger, B.L., “Simultaneous Measurement of Nineteen Binding Constants of Peptides to Vancomycin Using Affinity Capillary Electrophoresis-Mass Spectrometry”, J. Medicinal Chem., 41, 1201-1204 (1998).

Foret, F., Liu, H., Zhang, B., Felten, C. and Karger, B.L., "Microdevices for Electrospray Mass Spectrometry", Proceedings of the m TAS ’98 Workshop, eds., Harrison D. Jed and van den Berg, A., 35-38(1999).

Felten, C., Quan, C.P., Chen. A.B., Canova-Davis, E., McNerney, T., Goetzinger, W.K., Karger, B.L., "The Use of Acidic and Basic pH and Calcium Ion Addition in the Capillary Zone Electrophoretic Characterization of RHD (rhDNAse), A Complex Phosphoglycoprotein", J. Chromatogr. A, 853, 295-308 (1999).

Little, J., Hughes, D.E. and Karger, B.L., "A Powerful Screening Technology Utilizing Capillary Electrophoresis", American Biochemistry, 36, August 1999.

Ghabbour, E. A., Davies, G. (Eds.), Understanding Humic Substances: Advanced Methods, Properties and Applications, Royal Society of Chemistry, Cambridge (1999).

Xing, B., Mao, J., Hu, W-G., Schmidt-Rohr, K., Davies G., Ghabbour, E. A. “Evaluation of Different Solid State 13C NMR Techniques for Characterizing Humic Acids,” in Ghabbour, E. A., Davies, G. (Eds.), Understanding Humic Substances: Advanced Methods, Properties and Applications, Royal Society of Chemistry, Cambridge (1999) pp. 49-61.

Lan, Z-H, Wang, P., Giese, R.W., “Matrix-assisted Laser Desorption/Ionization Mass Spectrometry of Deoxynucleotides Labeled with an IMI Dye”, Rapid Commun. Mass Spectrom., 13, 1454-1457 (1999).

Marchev, K., Landis, M., Vallerio, R., Cooper, C.V. and Giessen, B.C., “The m Phase Layer on Ion Nitrided Austenitic Stainless Steel (III): An Epitaxial Relationship between the m Phase and the g Parent Phase, Surface and Coatings Technology”, 116-119 (1999).


Xi, Z., Jones, G. B., Qabaja, G., Wright, J. W., Johnson, F. S. and Goldberg, I. H., “Synthesis and DNA Binding of Spirocyclic Model Compounds Related to the Neocarzinostatin Chromophore”, Org. Lett., 1, 1375 (1999).

Siu-Caldera, M-L., Sekimoto, H., Weiskopf, A., Vouros, P., Bishop, J., Norman, A.W., Uskokovic, M.R., Schuster, I., and Reddy, G.S., "Studies of 1a,25(OH)2-3- epi-D3 Production in Two Osteosarcoma Cell Lines (UMR 106 and ROS 17/2.8): Existence of 3-Epimerization Pathway Independent of C-24 Oxidation Pathway", Bone, 34, 457-463 (1999).

Sekimoto, H., Siu-Caldera, M.-L., Weiskopf, A., Vouros, P., Muralidharan,. K.R., Okamura, W.H., Uskokovic, M.R. and Reddy, G.S., "1a, 25-dihydroxy-3-epi-vitamin D3: In vivo metabolite of 1a,25-dihydroxyvitamin D3 in rats", FEBS Letters, 448, 278-282 (1999).

Ding, J.-M. and Vouros, P., "Advances in Capillary Electrophoresis - Mass Spectrometry: recent developments in interfaces and applications", Anal. Chem. 71, 378A-385A (1999).

Gangl, E.T., Turesky, R.J. and Vouros, P. "Determination of the In-Vivo formed DNA Adducts of 2-Amino-3-methylimidazo[4,5-f]quinoline by Capillary Liquid Chromatography-microElectrospray Mass Spectrometry", Chem. Res. Toxicol., 12, 1019-1027 (1999).

Andrews, C.L., Vouros, P. and Harsch, A., "Analysis of DNA Adducts Using High Performance Separation Techniques Coupled to Electrospray Mass Spectrometry", J. Chromatogr., A, 856, 515-526 (1999).

Zhang, B., Liu, H., Karger, B.L. and Foret, F., "A Microdevice with Integrated Liquid Junction for Facile Peptide and Protein Analysis by Capillary Electrophoresis-Electrospray Mass Spectrometry", Anal. Chem., 72, 1015, (2000).

Foret, F., Zhou, H., Gangl, E. and Karger, B.L., "Subatmospheric Electrospray Interface for Coupling of Microcolumn with Mass Spectrometry", Electrophoresis Separations, 21, 1363, (2000).

Tim, R.C., Kautz, R.A. and Karger, B.L., "Ultratrace Analysis of Drugs in Biological Fluids Using Affinity Probe Capillary Electrophoresis: Analysis of Dorzolamide with Fluorescently Labeled Carbonic Anhydrase", Electrophoresis, 21, 220, (2000).

Zhou, H., Miller, A.W., Sosic, Z., Barron, A.E., Buchholz, B., Kotler, L. and Karger, B.L., "DNA Sequencing Up to 1300 Bases in Two Hours by Capillary Electrophoresis with Mixed Replaceable Linear Polyacrylamide Solutions", Anal. Chem., 72, 1045, (2000).

Minarik, M., Foret, F., Karger, B.L., "Fraction Collection in Micropreparative Capillary Zone Electrophoresis and Capillary Isoelectric Focusing", Electrophoresis, 21, 247, (2000).

Liu, H., Felten, C., Xue, Qifeng, Zhang, B., Jedrzejewski, P., Karger, B.L. and Foret, F., "Development of Multichannel Devices with an Array of Electrospray Tips for High-Throughput Mass Spectrometry", Anal. Chem., 72, 3303-3310 (2000).

Preisler, J., Hu, P., Rejtar, T. and Karger, B.L., "Capillary Electrophoresis – Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry Using a Vacuum Deposition Interface", Anal. Chem., 72, 4785-4795 (2000).

Hafner, F-T., Kautz, R.A., Iverson, B.L., Tim, R.C. and Karger, B.L., "Noncompetitive Immunoassay of Small Analytes at the Femtomolar Level by Affinity Probe Capillary Electrophoresis: Direct Analysis of Digoxin Using a Uniform-Labeled scFv Immunoreagent", Anal. Chem., 72, 5779-5786 (2000).

Lu, R.J., Giese, R.W., AMACE1: Versatile Aminoacetamide Electrophore Reagent, Anal. Chem., 72, 1798-1801 (2000).

Wang, P., Giese, R.W., Laser-Induced Electron Capture Mass Spectrometry, Anal. Chem., 72, 772-776 (2000).

Lu, R. J., Liu, D., Giese, R.W., Detritylation with Ytterbium Triflate, Tetrahedron Letters, 41, 2817-2819 (2000).

Bocek, P., Vespalec, R., Giese, R.W., Selectivity in CE, Anal. Chem., 72, 587A-595A (2000).

Giese, R. W., Electron-capture mass spectrometry: recent advances, J. Chromatogr., 892, 329-346, (2000).

Jones, G. B., Plourde, G. W., Wright, J. M. "Understanding Enediyne-Protein Interactions: Diyl Atom Transfer Results in Generation of Aminoacyl Radicals", Organic Letters, 2, 811 (2000).

abaja, G., Perchellet, E. M., Perchellet, J.-P. and Jones, G. B., Regioselective Lactonization of Naphthoquinones: Synthesis and Antitumoral Activity of the WS 5995 Antibiotics, , Tetrahedron Letters,, 41, 3007 (2000).

Qabaja, G. and Jones, G. B. Annulation Strategies in Benzo[b]quinone Synthesis: Efficient Routes to Kinafluorenone and the WS-599A Antibiotics. J. Org. Chem., 65, 7187 (2000).

Qabaja, G. and Jones, G. B. An Intramolecular Arylation Route to the Kinafluorenones, Tet. Lett., 41, 5317 (2000).

Jones, G. B. and Plourde, G. W. Electronic Control of the Bergman Cycloaromatization: Synthesis and Chemistry of Chloroenediynes, Org. Lett., 2, 1757 (2000).

Jones, G. B., Wright, J. M., Hynd, G., Wyatt, J. K., Yancisin, M. and Brown, M. A. Protein-degrading Enediynes: Library Screening of Bergman Cycloaromatization Products. Org. Lett., 2, 1863 (2000).

Jones, G. B. and Guzel, M. Exploiting p Shielding Interactions in a h-6 Arene Complexed Chiral Auxiliary. Tet. Lett., 41, 4695 (2000).

Jones, G. B. and Guzel, M. Catalytic Enantioslective Cycloadditions: A Readily Available Diels-Alder Catalyst. Tet. Asymm., 11, 1267 (2000).

Jones, G. B., Guzel, M. and Heaton, S. B. Enantioselective Catalysis using Planar Chiral h6 Arene Chromium Complexes: 1,2-Diols as Cycloaddition Catalysts. Tetrahedron: Asymmetry, 11, 4303 (2000).

Jones, G. B., Wright, J., Plourde II, G., Purohit, A. D., Wyatt, J. Hynd, G. and Fouad, F. “Photoactivated enediynes as Affinity Cleavage Agents”, J. Am. Chem. Soc., 122, 9872 (2000).

Jones, G. B., Mitchell, M. O., Weinberg J. S., D’Amico, A. V. and Bubley, G. A. An Enzyme Activated Antiprostatic Prodrug. Bioorg. Med. Chem. Lett., 10, 1987 (2000).

Jones, G. B. and Guzel, M. Catalytic Enantioselective Cycloadditions: A
Readily Available Diels-Alder Catalyst. Tet. Asymm., 11, 1267 (2000).

Posner, G.,H., Crawford, K., Caldera-Su, M.-L., Reddy, G.S., Sarabia, S., Feldman, D., Van Etten, E., Mathieu, C., Gennaro, L., Vouros, P., Peleg, S., Dolan, P., Kensler, T.W. “Conceptually New 20-Epi-22-oxa-sulfone Analogs of the Hormone 1,25-
Dihydroxyvitamin D3:Synthesis and Preliminary Biological Evaluation”, J. Med. Chem., 43, 3581-3586 (2000).

Marzilli, L.A., Koertje, C. and Vouros, P., “Capillary Electrophoresis – Mass Spectrometric
Analysis of DNA Adducts”, Methods in Molecular Biology, Humana Press Inc., 162, 395-406. (2000)

Harsch, A., Marzilli, L.A., Bunt, R.C., Stubbe, J. and Vouros, P., Accurate and Rapid Modeling of Iron-Bleomycin Induced DNA Damage using Tethered Duplex Oligonucleotides and Electrospray Tandem Mass Spectrometry, Nucleic Acids Research, 28, 1978-1985 (2000).

Ding, J.-M. and Vouros, P., Capillary Electrochromatography - Mass Spectrometry for the Separation and Identification of Isomeric PAH-DNA Adducts Derived from In Vitro Reactions. A Review, J. Chromatogr. A, 887, 103-110 (2000).

Ding, J.-M. and Vouros, P. Capillary electrochromatography – Mass spectrometry for the Separation and Identification of Isomeric PAH-DNA Adducts Derived from in vitro Reactions. A review, J. Chromatogr. A, 887, 103 (2000).

Harsch, A., Sayer, J. M., Jerina, D. M. and Vouros, P. HPLC-MS/MS Identification of Positionally Isomeric Benzo[c]phenanthrene Diol Epoxide Adducts in Duplex DNA. Chem. Res. Toxicol., 13, 1342 (2000).

Reddy, G. S , Rao, D. S., Siu-Caldera, M -L., Sekimoto, H., Astecker, N., Weiskopf, A., Vouros, P., Sasso, G. J., Manchand, P. S. and Uskokovic, M. R. 1a,25-dihydroxy-16-ene-23-yne-vitamin D3 and 1a,25-dihydroxy-16-ene-23-yne-20-epi-vitamin D3: Analogs of 1a-25-dihydroxyvitamin D3 that Resist Metabolism Through the C-24 Oxidation Pathway are Metabolized through the C-3 Epimerization Pathway. Archives Biochem. Biophys., 383, 197 (2000).

Felten, C., Foret, F., Minarik, M., Goetzinger, W. and Karger, B.L., "Automated High Throughput Infusion ESI-MS with Direct Coupling to a Microtiter Plate", Anal. Chem., 73, 1449-1454 (2001).

Kautz, R., Lacey, M.E., Wolters, A.M., Foret, F., Webb, A.G., Karger, B.L., Sweedler, J.V., J., "Sample Concentration and Separation for Nanoliter-Volume NMR Spectroscopy Using Capillary Isotachophoresis", Am. Chem. Soc., 123, 3159-3160 (2001).

Karger, B. L., "Reminiscenses of 40 Years in Separation Science", Chromatrography – A Century of Discovery, 1900-2000: The Bridge to the Sciences/Technology; eds., C.W. Gehrke, R.L. Wixom and E. Bayer; Elsevier Science B.V., Amsterdam, The Netherlands (2001).

Zhang, B., Foret, F. and Karger, B.L., "Development of an Automated Microdevice Coupled to a Microwell Plate for CE/ESI/MS Analysis", Anal. Chem., 73, 2675-2681 (2001).

Karger, B.L. and Hancock, W.S., "Foreward" (Report on 14th International Symposium on Microscale Separations and Analysis (HPCE ’01), J. Chromatogr. A., 924, 1 (2001).

Lazar, I.M., Foret, F. and Karger, B.L., "Microfabricated Devices: A New Sample Introduction Approach to Mass Spectrometry", Chapter in Methods in Enzymology Volume Biological Mass Spectrometry, submitted (2001).

Weber, I. and Jones, G. B. Bidendate Planar Chiral 6-Arene Tricarbonyl Chromium(0) Complexes: Ligands for Catalytic Asymmetric Alkene Hydrosilylation, Tetrahedron Lett. 42, 6983 (2001).

Jones, G. B. and Warner, P. M. Electronic Control of the Bergman Cyclization: The Remarkable Role of Vinyl Substitution. J. Amer. Chem. Soc., 123, 2134 (2001).

Jones, G. B. Shielding in Organic Synthesis, Tetrahedron, 57, 7999 (2001).

Perchellet, E. M., Sperfslage, B. and Qabaja, G., Jones, G.B. and Perchellet, J.-P. Quinone Isomers of the WS-5995 Antibiotics: Synthetic Antitumor Agents that Inhibit Macromolecule Synthesis, Anti-Cancer Drugs, 12, 401 (2001).

Jones, G. B. and Warner, P. M. Electronic Control of the Bergman Cyclization: The Remarkable Role of Vinyl Substitution, J. Amer. Chem. Soc., 123, 2134 (2001).

Jones, G. B. Hynd, G., Wright, J. M. Plourde II, G. W., Huber, Robert S., Mathews, J. E., Li, A. Kilgore, M.W. Yancisin, M. and Brown, M. Target Directed Enediynes: Designed Estramycins, J. Org. Chem., 66, 3688, (2001).

Weber, I. and Jones, G. B. Bidendate Planar Chiral 6-Arene Tricarbonyl
Chromium(0) Complexes: Ligands for Catalytic Asymmetric Alkene
Hydrosilylation, Tetrahedron Lett. 42, 6983 (2001).

Jones, G.B., Purohit, A., Wyatt, J., Swamy, N. and Ray, R. Photoactivated Enediyne-Estrogens as Photochemical Proteases, Tetrahedron Lett., 42, 8579 (2001).

Warner, P.M. and Jones, G.B. "Quinone Products from Bergman Cycloaromatization. The Role of Molecular Oxygen",. J. Org. Chem., 66, 8659 (2001).

Warner, P.M. and Jones, G.B. Butalene and Related Compounds-Aromatic or Antiaromatic? J. Am. Chem. Soc., 123, 10322 (2001).

Delaney, J. and Vouros, P. Liquid Chromatography Ion Trap Mass Spectrometric Analysis of Oligosaccharides using Permethylated Derivatives. Rapid Commun. Mass Spectrom., 15, 325 (2001).

Weiskopf, A. S., Vouros, P., Cunniff, J., Binderup, E., Bjoerkling, F., Binderup, L., White, M-C. and Posner, G. H. Examination of Structurally-selective Derivatization of Vitamin D3 Analogues by Electrospray Mass Spectrometry. J. Mass Spectrom., 36, 71 (2001).

Hauser-Fang, A.; Smith, W.; Vouros, P.; Gupta, R. CE-MS Characterization of a DNA Adduct Formed in vitro from 9-OH-BP-derived Epoxide with Deoxyguanosine. Biochem. Biophys. Res. Commun., 281, 383 (2001).

Gangl, E.T.; Turesky, R. J.; Vouros, P. Detection of in vivo Formed DNA Adducts at the Part-per-billion Level by Capillary Liquid Chromatography-Microeectrospray/Mass sectrometry. Anal. Chem., 73, 2397 (2001).

Soglia, J. R.; Turesky, R. J.; Paehler, A.; Vouros, P. Quantification of the Heterocylic Aromatic Amine DNA Adduct N-(Deoxyguanosin-8-yl)-2-amino-3-methylimidazo[4,5-7]quinoline in the Liver of Rats using Capillary Liquid Chromatography-Microelectrospray/Mass Spectrometry: A Dose Response Study. Anal. Chem., 73, 2819 (2001).

Siu-Caldera, M.-L., Rao, S.N., Astecker, N., Weiskopf, A., Vouros, P., Konno, K., Fuujishima, T., Takayama, H., Peleg, S. and Reddy, G.S. Tissue Specific Metabolism of 1,25-Dihydroxy-20-epi-Vitamin D3 Into New Metabolites With Significant Biological Activity: Studies in Rat Osteosarcoma Cells (UMR 106 and ROS 17/2.8). J. Cellular Biochem., 82, 599 (2001).

Gangl, E.T., Annan, M., Spooner, N. and Vouros, P. Reduction of Signal Suppresion Effects in EDI-MS Using a nanoSplitting Device. Anal. Chem., 73, 5635 (2001).

 

 

 


 

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